There are also late peaks in androgen production in the cortex, and more interestingly, the amount of androgen detected in the hippocampus and cortex is equal to or higher than that of the reproductively relevant regions Fig.
Exceedingly rare but recently discovered men with mutations in the aromatase gene or estrogen receptor. It has been presumed that sex differences in the hippocampus underlie the divergent responses of males versus females in stress and learning paradigms.
There is a delayed from birth peak in estradiol production in the cortex and the timing differs by several days in males versus females. J Neuroendocrinol. There is a small but significant increase in the percentage of CAH girls self-identifying as lesbian but the overwhelming majority of CAH girls identify as female regardless of sexual preference [ Meyer-Bahlburg, ].
Some argue that this renders the work in rodents meaningless as the primary hormone mediating the process is different.